This study, funded by the Health Research Council with the University of Auckland, University of Otago and some Maurice Wilkins Centre researchers focuses on better understanding the impact that gene variants, including a CREBRF variant, can have on the risk of developing type-2 diabetes and related metabolic conditions like gout, obesity, and heart disease. The aim is to assess how small differences in our genes affect body structure (height, muscle and fat mass)and how our bodies handle kai (metabolism). In the longer term the findings will contribute to improving treatment and prevention of these diseases. Participants are gifting their data through a mixed meal test and a Dexa scan of body composition.